Con el inicio del nuevo curso, la Universidad Adams se vuelve a llenar de novatos, los cuales llevan años dominando el campus. Un antiguo alumno llega a la Universidad con su hijo y al ver la situación de dominio de éstos decide cambiarlo. Un nuevo decano y un ex alumno con sus mismas ideas serán sus colaboradores. The third movie in the Nerds series: The nerds are now in control of the university, as a result of Lewis Skolnick and the rest's actions in the two previous movies. A new generation of sportsmen arrive, however, determined on winning the school back. The principle, himself an ex-nerd fighter, helps them, and the nerds return to suppression. Harold Skolnick needs help from his uncle Lewis, the hero of the first two movies. Lewis, however, are not too proud of his nerd past, and won't reveal any of it, much less help his nephew. However, his wife makes him change his mind, and with help from his friends from the first two movies, they start the fight to win the school back, using classic nerd tricks.