Después de perder a la chica de sus sueños, Wyatt y su pandilla de amigos deciden preparar las maletas y salir en el más loco y excéntrico viaje en carretera a Las Vegas para recuperarla. After losing the girl of his dreams to another man, Wyatt and his posse pack their suitcases and head out on the craziest, screwball road trip to Las Vegas to win her back. With less then twenty-seven hours to break up her wedding, they must make it before it is too late without falling apart at the seams and living up to their names... American Idiots!